MS14
نویسندگان
چکیده
منابع مشابه
MS14, a Marine Herbal Medicine, an Immunosuppressive Drug in Experimental Autoimmune Encephalomyelitis
BACKGROUND Cytokines are secreted signaling proteins which play essential roles in immune responses during experimental autoimmune encephalomyelitis (EAE), a demyelinating model that mimics many features of multiple sclerosis (MS). Interleukin 6 (IL-6) is a multifunctional cytokine produced by different cells, mediating inflammatory reactions and immune-mediated processes. Several studies have ...
متن کاملComparative genome‐wide analysis reveals that Burkholderia contaminans MS14 possesses multiple antimicrobial biosynthesis genes but not major genetic loci required for pathogenesis
Burkholderia contaminans MS14 shows significant antimicrobial activities against plant and animal pathogenic fungi and bacteria. The antifungal agent occidiofungin produced by MS14 has great potential for development of biopesticides and pharmaceutical drugs. However, the use of Burkholderia species as biocontrol agent in agriculture is restricted due to the difficulties in distinguishing betwe...
متن کاملMS14 Down-regulates Lipocalin2 Expression in Spinal Cord Tissue in an Animal Model of Multiple Sclerosis in female C57BL/6
BACKGROUND Experimental autoimmune encephalomyelitis (EAE) is an animal model of multiple sclerosis, which is a demyelinating and an inflammatory disease of central nervous system. Recent studies have established that some molecules such as Lipocaline2 (LCN2), which expresses during inflammatory conditions, play an important role in EAE pathogenesis and might involve in its treatment process. Re...
متن کاملGenetic and biochemical map for the biosynthesis of occidiofungin, an antifungal produced by Burkholderia contaminans strain MS14.
A striking feature of Burkholderia contaminans strain MS14 is the production of a glycolipopeptide named occidiofungin. Occidiofungin has a broad range of antifungal activities against plant and animal pathogens. In this study, a complete covalent structure characterization and identification of the whole genomic DNA region for the occidiofungin gene (ocf) cluster are described. Discovery of th...
متن کاملتأثیر فرآورده MS14 بر پاسخ ایمنی هومورال در موش Balb/c
سیستم ایمنی در اتیولوژی و پاتوفیزیولوژی بیماریهای متعددی دخالت میکند. بنابراین تعدیل پاسخهای ایمنی، ازجمله پاسخهای ایمنی هومورال میتواند در بهبود و کنترل این بیماریها مؤثر باشد. گیاهان دارویی بهعنوان یکی از منابع غنی ایمونومدولاتورها (تنظیمکنندههای پاسخ ایمنی) مطرح هستند. در این مطالعه به بررسی تأثیر فرآورده گیاهی- دریایی MS14 بر پاسخ ایمنی هومورال اولیه و ثانویه در موش پرداخته شده است. بر...
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ژورنال
عنوان ژورنال: Nihon Kessho Gakkaishi
سال: 2009
ISSN: 0369-4585,1884-5576
DOI: 10.5940/jcrsj.51.41